TCDA Expression

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Expression

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

Summary of PDG mRNA expression levels (FPKM value) in each cancer type

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HGNC	Ensembl	No. Detectable	ACC				BLCA				BRCA				CESC				CHOL				COAD				DLBC				ESCA				GBM				HNSC				KICH				KIRC				KIRP				LAML				LGG				LIHC				LUAD				LUSC				MESO				OV				PAAD				PCPG				PRAD				READ				SARC				SKCM				STAD				TGCT				THCA				THYM				UCEC				UCS				UVM
Symbol	Gene ID	Cancer Types	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th
UGT2A1	ENSG00000173610	0	0	0	0.02	0.05	0	0	0.04	0.14	0	0	0	0.03	0	0	0.03	0.25	0	0.02	0.08	0.18	0	0	0	0.03	0	0	0	0	0	0.03	0.09	0.35	0	0	0	0	0	0	0.05	0.2	0.01	0.04	0.14	0.38	0	0	0.03	0.11	0	0.05	0.27	0.94	0	0	0.01	0.1	0	0	0	0.02	0.04	0.22	1.15	4.21	0	0	0.07	0.22	0.02	0.11	0.48	2.55	0	0	0.02	0.06	0	0	0.02	0.1	0	0	0	0.02	0	0	0	0	0	0	0	0.01	0	0	0.01	0.06	0	0	0	0.04	0	0	0.01	0.05	0	0	0.03	0.09	0	0.03	0.07	0.14	0	0	0	0	0	0	0.01	0.05	0	0	0	0.05	0	0	0.03	0.06	0	0	0	0
OR3A1	ENSG00000180090	0	0	0	0.02	0.14	0	0	0	0.02	0	0	0.02	0.05	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0.03	0	0.03	0.05	0.09	0	0	0	0.03	0	0	0	0.03	0	0	0.02	0.05	0	0	0.01	0.04	0	0	0.04	0.52	0	0.02	0.04	0.06	0	0	0	0	0	0	0	0.04	0	0	0	0.03	0	0	0	0.02	0	0	0.02	0.1	0	0	0.02	0.03	0	0	0	0.04	0	0	0	0.03	0	0	0	0.02	0	0	0	0.03	0	0	0.02	0.07	0	0	0.01	0.05	0.06	0.16	0.33	0.48	0	0	0.01	0.04	0	0	0.04	0.11	0	0	0	0	0	0	0	0.03	0	0	0	0.03
OR2C3	ENSG00000196242	0	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0.04	0.16	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0.01	0.03	0	0	0	0.01	0	0	0	0	0	0.02	0.04	0.09	0	0	0	0	0	0	0	0.01	0	0.01	0.04	0.31	0	0	0.01	0.02	0.01	0.02	0.05	0.09	0	0	0	0	0	0.01	0.02	0.03	0	0	0	0	0	0	0	0.02	0	0	0.03	0.1
OR2M3	ENSG00000228198	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0.13	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
KCNK18	ENSG00000186795	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0
CDKL4	ENSG00000205111	0	0	0.03	0.22	0.75	0.02	0.04	0.1	0.3	0	0.03	0.06	0.12	0	0.04	0.11	0.31	0.04	0.11	0.18	0.29	0	0.02	0.05	0.1	0	0.05	0.16	0.24	0.02	0.05	0.1	0.21	0.03	0.07	0.13	0.24	0	0.01	0.03	0.09	0	0	0.03	0.05	0	0.03	0.07	0.18	0	0.03	0.11	0.27	0.03	0.09	0.24	0.57	0.02	0.04	0.08	0.14	0	0.01	0.04	0.1	0.01	0.05	0.1	0.25	0.01	0.04	0.09	0.22	0	0.02	0.04	0.09	0.02	0.06	0.14	0.3	0.02	0.04	0.09	0.21	0.02	0.06	0.18	0.44	0.01	0.03	0.07	0.14	0	0.02	0.04	0.09	0	0.02	0.06	0.13	0	0.03	0.08	0.2	0.01	0.05	0.11	0.18	0.08	0.18	0.33	0.59	0	0.03	0.07	0.17	0.02	0.04	0.09	0.13	0.03	0.08	0.26	0.53	0.02	0.11	0.24	0.59	0	0.02	0.04	0.12
OR5M11	ENSG00000255223	0	0	0	0	0	0	0.02	0.13	0.4	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0.04	0.09	0	0	0	0	0	0.01	0.06	0.14	0	0	0	0	0	0	0.03	0.08	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0.03	0.08	0.21	0	0	0	0	0	0	0	0.06	0	0	0	0.02	0	0	0	0	0	0	0	0.02	0	0	0.03	0.06	0	0	0	0	0	0	0	0	0	0	0.02	0.06	0	0	0.03	0.07	0	0	0	0	0	0	0.03	0.12	0	0	0	0.02	0	0	0	0	0	0	0	0
DEFB108B	ENSG00000184276	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.07	0.15	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0.05	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MAP3K19	ENSG00000176601	0	0	0	0.02	0.03	0	0.01	0.03	0.05	0	0.02	0.1	0.41	0	0.01	0.05	0.51	0	0.01	0.03	0.05	0	0	0.01	0.03	0	0	0	0.02	0.01	0.02	0.05	0.1	0.06	0.22	0.74	2.56	0	0.01	0.02	0.06	0	0	0.01	0.02	0	0.01	0.02	0.03	0	0	0.02	0.03	0.05	0.08	0.13	0.17	0.03	0.11	0.38	1.38	0	0	0.01	0.02	0.04	0.18	0.58	1.87	0.01	0.04	0.17	0.58	0	0	0.02	0.03	0.01	0.09	0.37	1.17	0	0.02	0.05	0.11	0	0.01	0.02	0.03	0.02	0.07	0.18	0.41	0	0	0.01	0.02	0	0	0.01	0.03	0	0	0.02	0.03	0	0.02	0.05	0.13	0.06	0.21	0.79	2.91	0	0	0.01	0.03	0	0.01	0.02	0.04	0.02	0.16	1.85	6.26	0	0.03	0.08	0.46	0	0	0	0.01
OR5V1	ENSG00000243729	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.15	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CELA2B	ENSG00000215704	1	0	0	0.08	0.25	0	0	0.02	0.08	0	0	0	0.02	0	0	0.02	0.07	0	0	0	0	0	0	0	0.03	0	0	0.03	0.08	0	0	0.03	0.06	0	0	0	0.07	0	0	0	0.06	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0.04	0.12	0	0	0.03	0.08	0	0	0	0.02	0	0	0.05	0.14	0	0	0.03	0.08	0	0	0.04	0.07	0	0	0.02	0.07	0.08	1.52	80.72	406.34	0	0	0.05	0.09	0	0	0	0.04	0	0	0	0.02	0	0	0.03	0.09	0	0	0	0.03	0	0	0.04	0.09	0	0	0.04	0.11	0	0	0	0.03	0	0	0	0.06	0	0	0	0.03	0	0	0.05	0.23	0	0	0	0
ADAM30	ENSG00000134249	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.02	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.01	0.03	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0.01	0.04	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0
OR10G2	ENSG00000255582	0	0	0	0	0	0	0	0	0.01	0	0	0.02	0.04	0	0	0	0.02	0	0	0	0.02	0	0	0	0.02	0	0	0.04	0.06	0	0	0	0.03	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0.07	0	0	0	0	0	0	0	0.02	0	0	0.03	0.07	0	0	0	0.02	0	0	0	0	0	0	0	0.01	0	0	0	0.02	0	0	0	0	0	0.01	0.04	0.09	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0.01	0.06	0	0	0.02	0.04	0	0	0	0.01	0	0.03	0.08	0.25	0	0	0	0.02	0	0	0	0	0	0	0	0
OR10A2	ENSG00000170790	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0.05	0	0.03	0.1	0.18	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0.03	0	0	0	0.02	0	0	0.21	0.7	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0	0	0	0	0	0	0.03	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0.02	0.07	0.15	0	0	0	0.02	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0
OR2J2	ENSG00000204700	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PCDHA2	ENSG00000204969	0	0.01	0.08	0.46	0.96	0	0.02	0.09	0.24	0.04	0.13	0.31	0.57	0	0.01	0.05	0.13	0	0.03	0.14	0.71	0	0.01	0.04	0.1	0	0	0.01	0.04	0	0.01	0.07	0.24	0.08	0.29	0.81	1.98	0	0	0.01	0.03	0.01	0.03	0.11	0.69	0.05	0.14	0.34	0.66	0.08	0.29	0.72	1.32	0	0	0.01	0.06	0.38	0.74	1.9	3.94	0	0.01	0.02	0.11	0.04	0.11	0.23	0.43	0.01	0.04	0.1	0.26	0.01	0.05	0.27	0.52	0.05	0.14	0.31	0.58	0.05	0.09	0.15	0.26	0.22	0.42	0.86	1.63	0.03	0.12	0.3	0.64	0	0.01	0.03	0.07	0	0.03	0.23	0.75	0.01	0.02	0.12	0.4	0.01	0.02	0.06	0.14	0.01	0.02	0.05	0.32	0.03	0.08	0.18	0.31	0	0	0.03	0.1	0.03	0.13	0.31	0.61	0.07	0.22	0.67	1.11	0	0.01	0.03	0.14
CPA5	ENSG00000158525	0	0	0	0.04	0.19	0.08	0.22	0.56	1.25	0.03	0.12	0.35	0.74	0.06	0.15	0.37	0.66	0.04	0.19	0.5	0.86	0	0.03	0.16	0.33	0.11	0.26	1.38	3.76	0.03	0.09	0.22	0.58	0.12	0.24	0.42	0.8	0.07	0.14	0.31	0.61	0	0	0.03	0.12	0	0.04	0.15	0.36	0	0.01	0.09	0.26	0	0.1	0.33	0.82	0.05	0.11	0.22	0.42	0	0.06	0.2	0.53	0.02	0.11	0.32	0.6	0.03	0.11	0.27	0.53	0.07	0.15	0.34	0.91	0.09	0.26	0.58	1.15	0.03	0.11	0.32	0.74	0.08	0.18	0.39	0.61	0	0.03	0.09	0.18	0.01	0.07	0.13	0.26	0.02	0.1	0.43	1.01	0.01	0.07	0.22	0.68	0.01	0.09	0.36	0.8	0.08	0.19	0.45	0.99	0.02	0.08	0.21	0.41	0.31	0.86	2.34	4.82	0.02	0.14	0.32	0.8	0.17	0.36	1.42	3.03	0	0	0.02	0.09
SPINK9	ENSG00000204909	0	0	0.05	0.17	0.41	0	0	0.05	0.11	0	0	0	0.05	0	0	0	0.07	0	0	0.01	0.08	0	0	0	0.06	0	0	0	0	0	0	0.05	0.1	0	0	0.03	0.09	0	0	0.06	0.19	0	0	0.03	0.11	0	0	0.05	0.12	0	0	0.03	0.08	0	0	0.07	0.13	0	0	0.05	0.13	0	0	0	0.06	0	0	0.1	0.27	0	0	0.05	0.12	0	0	0	0.04	0	0	0.03	0.09	0	0	0.06	0.13	0	0	0.06	0.19	0	0	0.09	0.17	0	0	0	0.06	0	0	0	0.07	0	0	0	0.06	0	0	0.03	0.06	0	0	0	0.07	0	0.04	0.12	0.24	0	0.05	0.13	0.23	0	0	0.09	0.46	0	0	0.08	0.22	0	0	0	0.04
INS-IGF2	ENSG00000129965	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.1	1.45	0	0	0	0	0	0	0	0	0	0	0	0	0	0.09	0.18	0.29	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0.09	0.17	0.27	0	0	0.23	1.98	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.03	0.17	0.04	0.51	2.77	7.87	0	0.1	0.32	0.8	0	0	0	0	0	0	0	0	0	0	0	0.05	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.07	0.23	0	0	0	0
OR1C1	ENSG00000221888	0	0	0	0	0	0	0	0	0	0	0	0.02	0.05	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0.08	0.17	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0.07	0	0	0	0	0	0	0	0	0	0.02	0.05	0.09	0	0	0	0	0	0	0	0.05	0	0	0	0.02	0	0	0	0	0	0.02	0.06	0.12	0	0	0	0.02	0	0	0	0.03	0	0	0.01	0.06	0	0	0.02	0.05	0	0	0	0.03

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