TCDA Expression

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Expression

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

Summary of PDG mRNA expression levels (FPKM value) in each cancer type

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HGNC	Ensembl	No. Detectable	ACC				BLCA				BRCA				CESC				CHOL				COAD				DLBC				ESCA				GBM				HNSC				KICH				KIRC				KIRP				LAML				LGG				LIHC				LUAD				LUSC				MESO				OV				PAAD				PCPG				PRAD				READ				SARC				SKCM				STAD				TGCT				THCA				THYM				UCEC				UCS				UVM
Symbol	Gene ID	Cancer Types	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th
SLC25A21	ENSG00000183032	1	0.14	0.49	0.76	1.59	0.08	0.2	0.39	0.72	0.28	0.56	1.03	1.61	0.2	0.35	0.64	1.08	0.17	0.53	0.89	1.23	0.04	0.16	0.49	1.12	0	0.01	0.03	0.06	0.18	0.38	0.8	1.26	0.02	0.04	0.14	0.62	0.14	0.28	0.54	0.97	0.16	0.28	0.58	1.01	0.23	0.43	0.74	1.12	0.23	0.43	0.73	1.17	0	0.06	0.29	0.86	0.3	0.5	0.82	1.17	0.03	0.11	0.22	0.43	0.32	0.58	1.14	2.27	0.28	0.56	1.07	1.88	0.11	0.24	0.5	0.86	0.07	0.16	0.28	0.44	0.22	0.37	0.6	1.03	0.13	0.18	0.37	0.54	0.69	0.99	1.4	1.81	0.02	0.11	0.23	0.63	0.06	0.27	0.78	1.82	0.01	0.18	0.7	1.68	0.08	0.24	0.6	1.07	0.43	0.72	1.19	1.7	0.55	0.76	1.04	1.33	0.87	1.33	2.46	4.49	0.11	0.26	0.64	1.11	0.34	0.71	1.13	2.17	0.03	0.13	0.6	1.16
CST9L	ENSG00000101435	0	0	0	0	0	0	0	0	0.02	0	0	0.14	0.78	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0.02	0.06	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0.05	0.48	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0.01	0	0	0	0
EYS	ENSG00000188107	0	0.02	0.05	0.13	0.28	0.01	0.02	0.05	0.15	0.03	0.05	0.09	0.17	0.02	0.02	0.05	0.13	0.04	0.09	0.15	0.23	0.03	0.05	0.1	0.27	0.01	0.02	0.04	0.05	0.06	0.11	0.2	0.32	0.01	0.03	0.06	0.15	0.02	0.03	0.06	0.12	0.01	0.03	0.05	0.1	0.04	0.06	0.09	0.12	0.02	0.04	0.07	0.13	0.27	0.47	0.66	1.31	0.04	0.07	0.15	0.29	0.07	0.21	0.57	1.16	0.09	0.23	0.71	1.7	0.04	0.1	0.27	0.66	0.02	0.03	0.05	0.07	0.02	0.03	0.05	0.09	0.06	0.11	0.17	0.26	0.09	0.18	0.51	1.73	0.04	0.06	0.11	0.21	0.04	0.06	0.09	0.21	0.02	0.02	0.05	0.11	0.01	0.02	0.05	0.09	0.06	0.11	0.18	0.37	0.06	0.16	0.39	0.66	0.03	0.04	0.05	0.07	0.04	0.06	0.09	0.16	0.02	0.03	0.04	0.07	0.02	0.03	0.04	0.08	0.01	0.01	0.02	0.03
OR51A4	ENSG00000205497	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR2T33	ENSG00000177212	0	0	0	0	0	0	0	0	0	0	0	0.02	0.08	0	0	0	0.02	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0.02	0	0	0	0	0	0	0	0.02	0	0	0	0	0.06	0.23	0.41	0.65	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.05	0.08	0	0.03	0.1	0.25	0	0	0	0	0	0	0	0.03	0	0	0.05	0.1	0	0	0	0.01	0	0	0	0.03	0	0	0	0.03	0	0	0	0.01	0	0	0	0.05	0	0.03	0.11	0.24	0	0	0.02	0.08	0	0	0	0.1	0	0	0	0.07	0	0	0	0.02
MSMP	ENSG00000215183	3	0.08	0.22	0.39	0.5	0.07	0.18	0.35	0.72	0.05	0.13	0.26	0.44	0	0.06	0.14	0.3	0.17	0.41	1.01	2.23	0.17	0.29	0.5	0.77	0.9	1.96	3.89	8.52	0	0.1	0.24	0.41	1.97	3.7	6.73	18.74	0	0.07	0.16	0.3	0.18	0.28	0.48	0.74	0.27	0.5	0.85	1.42	0.22	0.53	1.25	5.09	0	0	0.19	0.4	0.36	0.6	1.29	3.61	0	0.1	0.21	0.39	0.15	0.27	0.46	0.69	0	0.09	0.21	0.34	0.08	0.25	0.38	0.91	0.28	0.55	1.04	1.78	0.11	0.24	0.45	0.77	0.37	0.58	0.96	1.57	0.1	0.23	0.45	0.8	0.2	0.33	0.52	0.77	0.06	0.17	0.42	0.8	0.06	0.19	0.56	2.36	0.08	0.2	0.39	0.7	0.08	0.21	0.43	0.71	0.86	1.33	2.13	4.46	0.07	0.13	0.26	0.53	0.19	0.42	0.73	1.55	0.18	0.7	1.67	3.26	0.17	0.37	0.63	1.29
SERPINB12	ENSG00000166634	0	0	0	0	0.04	0	0	0.03	0.12	0	0	0	0.02	0	0.06	0.66	7.79	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.27	1.19	0	0	0	0	0.04	0.17	0.81	3.22	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.02	0.13	0.7	3.62	0	0	0	0	0	0	0	0.04	0	0	0	0.02	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0.01	0	0	0.01	0.07	0	0	0	0.03	0	0.02	0.12	0.45	0	0	0	0	0	0	0.07	1.85	0	0	0	0.04	0	0	0.05	0.16	0	0	0	0.02
LALBA	ENSG00000167531	0	0	0	0	0	0	0	0	0.02	0	0	0	0.08	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0	0	0.08	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0.03	0.07	0.14	0	0	0	0	0	0	0	0.03	0	0	0	0.03	0	0	0	0.04	0	0	0	0
OR5P2	ENSG00000183303	0	0	0	0	0	0	0	0.02	0.05	0	0	0	0.02	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.03	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR6N1	ENSG00000197403	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.05	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MAS1	ENSG00000130368	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0.01	0.02	0.06	0	0	0	0.01	0	0	0.02	0.05	0	0	0.01	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0.02	0.09	0.26	0	0.02	0.1	0.37	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0.01	0.01	0.03	0	0	0.01	0.05	0	0	0	0	0	0	0	0	0	0.01	0.02	0.03	0	0	0	0.01	0	0.01	0.03	0.11	0	0	0	0.02	0	0	0.01	0.02	0.01	0.03	0.09	0.21	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.01	0.03	0	0	0	0
GUCY1B2	ENSG00000123201	0	0	0	0.02	0.65	0.1	0.32	0.76	1.54	0.02	0.12	0.51	1.3	0.11	0.36	0.88	1.63	0.01	0.11	1.55	3.28	0.1	0.23	0.48	0.94	0.04	0.13	0.25	0.52	0.2	0.59	1.1	1.9	0.01	0.03	0.09	0.21	0.02	0.12	0.32	0.59	0	0	0.01	0.1	0.01	0.05	0.69	2.29	0.01	0.04	0.72	1.88	0.07	0.14	0.26	0.62	0.01	0.05	0.13	0.24	0	0.04	0.3	0.77	0.31	0.81	1.81	3.36	0.12	0.38	0.82	1.42	0.01	0.02	0.31	0.94	0.13	0.4	0.93	1.53	0.11	0.46	0.93	1.64	0	0	0.01	0.03	0	0.01	0.08	0.35	0.07	0.23	0.41	0.61	0	0.01	0.07	0.22	0	0.01	0.09	0.36	0.08	0.24	0.49	1.06	0.01	0.05	0.16	0.42	0	0.01	0.01	0.05	0.02	0.1	0.8	1.52	0.07	0.52	1.18	2.41	0.09	0.41	0.96	1.55	0	0	0.01	0.1
OR10J6P	ENSG00000158731	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.33	0.94	2.34	6.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0.03	0	0	0	0	0	0	0	0	0.15	0.54	1.45	3.13	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0.02	0.13	0.32	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PRSS30P	ENSG00000172460	0	0.08	0.19	0.58	1.42	0.17	0.36	0.86	2.28	0.14	0.26	0.45	0.85	0.13	0.26	0.51	1.03	0.15	0.23	1.12	2.37	0.19	0.37	0.93	2.24	0.2	0.33	0.56	1.15	0.05	0.12	0.38	1.09	0.09	0.16	0.32	0.58	0.06	0.12	0.22	0.41	0.04	0.11	0.29	0.65	0.19	0.35	0.61	0.95	0.08	0.15	0.32	0.78	0.11	0.25	0.47	0.86	0.09	0.15	0.28	0.53	0.04	0.1	0.2	0.37	0.12	0.24	0.54	1.29	0.09	0.17	0.33	0.75	0.09	0.18	0.42	1.41	0.12	0.26	1.19	3.37	0.33	0.51	0.87	2.06	0.07	0.19	0.36	0.54	0.08	0.14	0.22	0.33	0.25	0.61	1.2	2.52	0.1	0.29	0.69	1.46	0.09	0.33	1.38	3.46	0.13	0.25	0.63	1.91	0.28	0.47	0.75	1.21	0.18	0.44	1.01	1.66	0.12	0.32	1.17	2.27	0.13	0.22	0.47	0.94	0.11	0.24	0.63	2.72	0.07	0.31	0.64	1.43
PRSS41	ENSG00000215148	0	0	0	0	0	0	0	0.04	0.44	0	0	0	0.08	0	0	0.01	0.06	0	0	0.02	0.06	0	0.04	0.12	0.25	0	0	0	0	0	0.02	0.09	0.25	0	0	0	0	0	0	0.02	0.04	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0.02	0.06	0	0	0.02	0.06	0	0	0	0	0	0	0.05	0.17	0	0.03	0.1	0.4	0	0	0	0	0	0	0	0.04	0.02	0.05	0.16	0.35	0	0	0	0	0	0	0	0.03	0	0.02	0.1	0.44	0.19	0.56	1.22	1.97	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0.03	0	0	0	0
ADGRE4P	ENSG00000268758	0	0.02	0.04	0.1	0.17	0.02	0.05	0.1	0.19	0.04	0.08	0.15	0.28	0.03	0.07	0.14	0.23	0.04	0.09	0.19	0.32	0.02	0.06	0.14	0.35	0.04	0.07	0.26	0.58	0.04	0.08	0.15	0.32	0.22	0.38	0.66	1.19	0.03	0.06	0.12	0.2	0.01	0.03	0.07	0.1	0.09	0.19	0.41	0.78	0.06	0.13	0.26	0.5	0.3	0.96	2.87	8.15	0.11	0.23	0.51	0.92	0.02	0.05	0.09	0.18	0.11	0.24	0.5	0.87	0.06	0.12	0.24	0.48	0.09	0.15	0.29	0.43	0.02	0.05	0.11	0.23	0.08	0.15	0.28	0.4	0.02	0.04	0.07	0.11	0.02	0.04	0.08	0.14	0.02	0.07	0.13	0.21	0.02	0.07	0.18	0.36	0.03	0.06	0.15	0.28	0.04	0.09	0.18	0.33	0.07	0.13	0.26	0.5	0.03	0.08	0.16	0.26	0.07	0.14	0.31	0.57	0.01	0.03	0.07	0.12	0.01	0.03	0.06	0.12	0	0.01	0.04	0.14
AADACL2	ENSG00000197953	0	0	0	0	0	0	0	0.04	0.26	0	0	0	0.01	0	0.01	0.06	0.49	0	0	0	0.01	0	0	0	0.02	0	0	0	0	0	0.03	0.18	0.65	0	0	0	0	0.01	0.07	0.58	2.03	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0.01	0.03	0	0	0	0	0	0	0	0	0	0	0	0.02	0.01	0.09	0.48	1.98	0	0	0	0.02	0	0.01	0.02	0.06	0	0	0	0.02	0	0	0	0.02	0	0	0	0	0	0	0	0.01	0	0	0.01	0.12	0	0	0	0.04	0	0	0.01	0.05	0	0	0.01	0.03	0	0	0	0	0	0	0.02	0.13	0	0	0.01	0.02	0	0	0	0.04	0	0	0	0
GPR101	ENSG00000165370	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.02	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0.06	0.2	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0.02	0.16	0	0	0	0.02	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0.04	0	0	0	0
SPINT4	ENSG00000149651	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PRSS58	ENSG00000258223	0	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0.05	0.12	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0.03	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0

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