TCDA Expression

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Expression

Positive expression of a PDG in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

Summary of PDG mRNA expression levels (FPKM value) in each cancer type

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HGNC	Ensembl	No. Detectable	ACC				BLCA				BRCA				CESC				CHOL				COAD				DLBC				ESCA				GBM				HNSC				KICH				KIRC				KIRP				LAML				LGG				LIHC				LUAD				LUSC				MESO				OV				PAAD				PCPG				PRAD				READ				SARC				SKCM				STAD				TGCT				THCA				THYM				UCEC				UCS				UVM
Symbol	Gene ID	Cancer Types	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th
CAPN14	ENSG00000214711	0	0	0	0.01	0.02	0.07	0.24	0.61	1.36	0.03	0.06	0.11	0.21	0.11	0.32	1.43	5.86	0.01	0.03	0.07	0.23	0.02	0.04	0.12	0.26	0.19	0.37	0.64	0.99	0.08	0.26	1.82	12.85	0.04	0.06	0.1	0.18	0.12	0.38	2.09	6.46	0	0	0.01	0.03	0.04	0.11	0.3	0.8	0.01	0.02	0.06	0.12	0.13	0.32	0.6	1.01	0.06	0.09	0.14	0.23	0	0.01	0.02	0.06	0.04	0.09	0.18	0.49	0.14	0.31	0.87	2.88	0.01	0.01	0.04	0.06	0.05	0.1	0.16	0.25	0.03	0.05	0.09	0.17	0.08	0.14	0.21	0.31	0.03	0.06	0.1	0.15	0.01	0.03	0.07	0.16	0.01	0.02	0.05	0.08	0.04	0.16	0.35	0.56	0.02	0.04	0.1	0.23	0.03	0.08	0.13	0.22	0.01	0.01	0.02	0.04	0.07	0.11	0.18	0.28	0.04	0.1	0.21	0.48	0.04	0.08	0.13	0.2	0.07	0.14	0.23	0.33
SCYL2	ENSG00000136021	33	6.65	9.56	13.13	17.19	7.27	9.81	13.19	16.27	10.12	13.69	17.79	22.67	8.57	11.51	14.37	17.43	5.86	8.75	10.54	12.58	10.1	12.15	14.35	17.32	2.81	6.11	8.79	12.75	14.35	17.99	22.6	28.6	8.56	10.45	12.68	14.51	9.74	12.47	15.52	18.64	7.02	11.49	14.72	17.37	6.28	8.07	10.14	12.4	6.43	9.24	12.96	15.46	20.19	24.82	29	33.99	6.43	8.06	10.1	12.24	3.68	5.58	7.89	10.02	9.9	12.92	15.95	19.9	11.28	14.1	17.26	21.23	6.53	8.02	10.25	11.96	6.22	8.97	11.8	14.91	6.85	9.15	11.29	13.41	4.73	6.3	7.76	9.05	8.37	10.95	13.93	17.07	9.88	12.77	15.55	17.72	5.27	7.77	10.59	13.4	6.47	9.54	12.67	16.08	11.34	14.26	17.71	21.7	6.07	8.64	10.42	12.23	7.24	8.89	10.52	12.17	4.1	6.19	8.72	10.99	5.97	9.08	13.07	15.87	5.18	7.34	10.04	12.1	1.99	3.5	5.66	8.09
PROKR2	ENSG00000101292	0	0	0	0	0.02	0	0	0	0.03	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0.05	0	0	0	0.02	0	0	0.02	0.08	0	0	0	0	0	0	0.02	0.07	0	0	0.03	0.1	0	0	0	0.02	0	0	0.04	0.09	0	0.04	0.1	0.36	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0	0	0.02	0	0.02	0.1	0.38	0	0	0	0.02	0	0	0	0.02	0	0	0	0.03	0	0	0	0	0	0	0.01	0.05	0	0	0.03	0.1	0	0	0	0.03	0.02	0.06	0.19	0.56	0	0	0	0.02	0	0.01	0.08	0.24	0	0	0	0.1	0	0	0.11	0.81	0	0	0	0.03
KIR3DL2	ENSG00000240403	0	0	0	0.04	0.11	0	0.01	0.06	0.14	0	0.04	0.09	0.22	0	0.07	0.2	0.51	0.01	0.05	0.09	0.18	0	0.02	0.06	0.15	0.03	0.1	0.38	0.85	0.01	0.03	0.09	0.14	0	0	0.02	0.05	0	0.04	0.11	0.25	0.01	0.03	0.05	0.09	0.06	0.13	0.25	0.4	0	0.02	0.06	0.11	0.06	0.14	0.36	0.66	0	0	0.01	0.02	0	0.02	0.04	0.1	0.02	0.07	0.15	0.31	0.02	0.05	0.12	0.27	0.01	0.05	0.12	0.21	0	0.02	0.06	0.12	0	0.02	0.05	0.09	0	0	0.03	0.05	0	0.03	0.07	0.14	0	0.01	0.04	0.06	0	0.01	0.06	0.13	0	0.04	0.13	0.29	0.03	0.07	0.2	0.39	0.05	0.15	0.43	0.9	0	0.02	0.06	0.13	0.04	0.14	0.28	0.5	0	0.03	0.07	0.16	0	0	0.01	0.04	0	0	0.02	0.04
HIST1H3I	ENSG00000275379	0	0	0	0	0.09	0	0.1	0.23	0.47	0	0	0.06	0.15	0	0.11	0.2	0.44	0	0	0.09	0.16	0	0.08	0.18	0.39	0.14	0.27	0.89	2.24	0.07	0.16	0.3	0.46	0	0	0.14	0.29	0	0.07	0.16	0.3	0	0	0	0	0	0	0	0.06	0	0	0	0.07	0	0.19	0.46	0.76	0	0	0	0.07	0	0	0.08	0.17	0	0	0.1	0.26	0	0.02	0.15	0.33	0	0	0.07	0.18	0.1	0.3	0.64	1.63	0	0	0.08	0.18	0	0	0	0.08	0	0	0	0.09	0	0.07	0.14	0.2	0	0	0.11	0.24	0	0	0.06	0.14	0.06	0.24	0.5	0.99	0	0.1	0.23	0.44	0	0	0	0.08	0.1	0.39	0.82	1.26	0	0.08	0.23	0.45	0	0.1	0.26	0.69	0	0	0.03	0.11
JADE2	ENSG00000043143	33	10.61	13.53	20.13	30.15	3.56	5.63	8.46	12.63	5.83	9.57	14	18.3	4.77	7.35	11.05	17.96	8.59	10.19	14.44	18.57	6.17	8.29	10.79	14.21	15.22	20.39	29.53	38.18	9.07	14.11	20.72	36.12	3.07	4.24	6.34	8.68	5.86	11.06	19.5	32.59	7.6	14.31	22.08	24.82	9.44	12.71	16.94	20.8	8.09	10.58	15.4	21.17	15.62	20.53	26.4	33.69	6.15	8.22	10.63	14	2.26	3.32	4.78	6.82	7.01	10.33	13.79	18.4	6.16	9.73	17.07	27.99	6.49	9.71	12.29	16.69	5.34	9.19	15.18	22.06	8.17	11.66	14.17	17.5	9.86	14.15	19.93	26.03	4.24	6.05	8.09	10.98	5.72	7.36	10.04	12.06	4.91	7.74	11.55	17.12	8.79	13.42	19.13	28.31	8.19	12.83	20.8	28.38	11.81	17.87	25.52	32.67	10.27	12.71	15.82	18.57	9.91	13.75	18.6	27.35	2.29	3.93	5.93	7.89	2.1	3.55	6	8.03	9.49	13.62	16.69	18.99
IFNA14	ENSG00000228083	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ZP1	ENSG00000149506	0	0.05	0.15	0.81	2.11	0.06	0.14	0.44	1.04	0.04	0.08	0.18	0.4	0	0.03	0.06	0.14	0	0.03	0.06	0.1	0.01	0.04	0.08	0.12	0	0.01	0.04	0.08	0.01	0.04	0.09	0.18	0.1	0.19	0.34	0.54	0.01	0.04	0.11	0.32	0	0.01	0.03	0.04	0.03	0.09	0.33	1.02	0	0.02	0.07	0.27	0	0.04	0.11	0.19	0.04	0.07	0.14	0.2	0	0.01	0.04	0.07	0.02	0.07	0.14	0.29	0.02	0.06	0.14	0.28	0.01	0.05	0.13	0.21	0.02	0.05	0.13	0.23	0.07	0.13	0.23	0.45	0.04	0.07	0.14	0.3	0.2	0.42	0.87	2.11	0.01	0.06	0.1	0.16	0.04	0.13	0.49	2.02	0.01	0.07	0.32	1.1	0.02	0.06	0.11	0.22	0	0.02	0.05	0.09	0.01	0.05	0.11	0.22	0.21	0.98	1.88	2.51	0	0.03	0.11	0.22	0.03	0.06	0.19	0.34	0	0.02	0.11	0.26
HTR6	ENSG00000158748	0	0	0	0.01	0.02	0	0	0.02	0.04	0	0.01	0.03	0.09	0	0.01	0.03	0.06	0	0	0	0.01	0	0.01	0.02	0.03	0	0.01	0.08	0.18	0.01	0.04	0.07	0.14	0	0.03	0.07	0.18	0	0.01	0.02	0.05	0	0	0.01	0.01	0.03	0.2	0.7	1.97	0	0	0.01	0.03	0.05	0.09	0.15	0.23	0.02	0.07	0.22	0.42	0	0	0	0.01	0	0.01	0.03	0.06	0.01	0.02	0.05	0.1	0	0.01	0.03	0.06	0.02	0.04	0.1	0.28	0	0.01	0.02	0.05	0	0.02	0.1	0.47	0.01	0.02	0.04	0.07	0	0.01	0.02	0.03	0	0.02	0.05	0.18	0	0.01	0.03	0.13	0.02	0.04	0.07	0.15	0.04	0.09	0.22	0.56	0	0	0.01	0.02	0	0	0.01	0.02	0	0.02	0.14	0.46	0.04	0.14	0.58	1.17	0	0.01	0.02	0.03
C8A	ENSG00000157131	2	0	0	0	0	0	0	0	0.03	0	0	0	0.01	0	0	0	0.01	0.31	1.19	8.96	31.51	0	0	0	0.01	0	0	0	0.03	0	0	0.01	0.05	0	0	0	0.01	0	0	0	0.01	0	0	0.01	0.01	0	0	0.01	0.01	0	0	0.01	0.02	0	0	0	0	0	0	0	0.01	29.78	65.76	110.81	167.67	0	0.02	0.08	0.4	0	0	0.01	0.05	0	0	0	0.01	0	0	0	0.01	0.02	0.06	0.15	0.36	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0.01	0.04	0	0	0	0.01	0	0.01	0.06	0.19	0	0	0.02	0.26	0.01	0.02	0.09	0.31	0	0	0	0.01	0	0.01	0.03	0.08	0	0	0.01	0.03	0	0	0	0
RNASE6	ENSG00000169413	33	1.48	4.27	7.56	16.2	1.93	4.78	10.87	21.86	7.55	11.82	17.72	26.33	3.25	5.82	10.53	18.12	4.26	8.3	13.94	22.72	5.36	8.03	11.48	15.15	13.13	20.12	31.49	49.66	2.62	5.25	9.06	14.13	13.12	21.84	31.64	47.4	3.17	6.19	11.11	17.78	1.91	3.75	7.32	12.52	12.56	19.98	29.14	37.81	4.71	8.39	16.54	26.82	6.83	28.28	80.83	133.28	5.15	8.93	15.42	25.71	2.33	4.16	8	12.32	9.64	15.54	22.41	33.63	4.85	9.02	15.78	23.28	11.81	19.7	25.85	39.15	5.19	9.83	15.84	24.42	7.92	13.57	24.23	40.76	2.49	4.57	7.56	11.99	3.78	5.71	8.85	12.26	5.78	8.33	11.4	16.24	6.61	15.68	35.77	62.43	4.94	9.95	19.21	30.29	5.75	10.96	19.73	33.66	7.1	12.05	18.55	26.11	2.86	5.09	9.21	15.6	16.99	21.42	30.19	38.81	2.98	5.54	8.54	13.79	3.22	4.64	8.76	13.96	1.76	3.09	7.25	12.1
GGT7	ENSG00000131067	33	2.98	5.38	8.57	15.49	4.76	7.87	13.02	18.97	3.58	5.94	8.95	13.54	3.62	7.03	11.6	16.14	6.97	12.42	17.96	23.08	4.01	8.3	13.22	18.71	1.51	2.21	3.6	5.4	2.21	4.55	7.42	9.73	12.69	16.29	21.04	27.96	1.61	3.36	5.9	9.42	8.35	9.74	11.85	14.04	5.21	7.18	9.4	11.71	5.89	8.38	11.57	15.36	1.33	2.52	3.99	6.44	11.75	15.16	18.91	23.43	3.34	4.82	6.94	9.69	5.8	8.94	13.36	18.36	5.29	7.65	11.91	17.13	2.34	4.1	5.9	9.61	7.82	11.82	17.11	23.57	7.08	9.54	12.6	15.6	9.2	11.76	14.98	17.72	5.91	9.65	13.83	17.33	7.01	9.84	15.14	19.93	4.24	7	10.31	14.97	7.47	10.85	15.09	21.25	2.52	4.35	7.61	12.29	5.46	7.22	9.24	11.73	9.17	11.53	14.17	17.12	7.2	9.04	11.17	14.79	5.4	9.57	13.77	18.45	9.39	11.66	15.67	21.1	5.38	6.3	8.1	9.45
MTMR4	ENSG00000108389	33	4.19	7.32	11.3	17.94	6.51	8.89	12.94	18.7	8.18	11.49	15.47	21.69	5.72	7.91	10.71	13.32	6.82	8.68	10.09	12.47	6.86	8.79	11.07	13.52	5.4	7.58	13.44	16.83	7.65	9.78	13.18	17.1	7.93	10.12	13.16	16.42	4.33	6.11	8.78	11.27	3.97	5.39	6.74	8.81	5.52	7.05	9.08	11.83	6.42	7.96	10.78	13.21	13.89	17.21	21.42	24.68	10.05	12.23	14.8	17.21	5.82	8.73	13.91	20.28	7.22	9.53	12.63	15.47	7.82	10.04	14.29	18.05	4.73	6.76	8.75	10.93	4.87	6.82	9.92	13.37	4.62	5.91	7.65	9.19	5.84	7.75	9.88	12.72	6.56	8.32	10.51	12.18	6.42	8.32	10.66	12.41	4.01	6.26	9.33	12.44	7.83	10.41	13.93	18.24	6	8.81	11.58	14.26	6.86	9.09	12.8	14.39	3.91	5.15	7.18	9.32	6	7.78	10.57	12.87	5.26	7.67	9.62	12.41	6.37	7.99	10.1	12.74	4.53	6.1	8.34	10
SLC44A1	ENSG00000070214	33	3.88	6.3	8.98	15.46	8.47	11.93	17.1	25.13	14.41	20.4	28.45	37.4	11.15	14.29	19.02	23.19	6.94	9.61	11.72	20.3	18.21	22.19	25.97	31.28	3.69	5.68	7.86	12.32	18.4	25.14	34.8	52.09	20.93	29	51.56	84.02	14.29	20.54	28.8	39.92	7.35	11.58	17.34	22.28	7.95	11.76	16.05	19.82	4.47	6.03	8.79	12.68	8.19	16.7	25.91	40.47	36.08	50.73	69.69	89.15	7.1	10.24	13.87	18.68	9.89	13.28	17.66	23.46	13.37	19.17	27.63	37.73	8.37	10.84	14.91	24.04	6.98	9.64	13.37	16.96	13.27	17.95	23.78	32.42	3.05	3.82	4.72	5.63	5.54	7.45	9.97	12.91	20.14	23.76	28.24	34.82	6.96	9.2	14.85	21.58	7.12	11.17	17.59	25.61	14.23	20.58	27.78	35.32	6.93	9.39	12.49	15.71	15.47	20.01	27.34	34.41	5.62	7.39	10	14.83	7.23	10.15	14.08	18.54	5.5	7.12	9.63	11.73	1.2	2.19	3.34	4.91
SPCS1	ENSG00000114902	33	104.38	133.18	167.6	216.17	116.23	152.01	213.87	293.67	115.67	147.35	180.56	217.39	81.92	108.27	141.38	174.3	88.58	99.51	110.76	143.34	113.79	133.43	161.55	188.18	101.03	117.18	157.39	183.28	56.73	71.73	95.12	118.85	127.48	152.38	176.69	213.51	64.34	77.02	94.39	118.08	92.68	143.81	176.52	199.67	59.95	69.6	82.51	105.18	100.58	122.14	146.76	172.24	54.74	68.54	82.03	96.97	96.97	111.66	126.16	145.71	115.64	145.39	187.11	234.44	100.35	121.43	145.83	182.85	83.69	98.64	119.91	145.22	82.1	102.57	136.48	157.06	110.04	145.39	182.3	223.02	100.58	114.14	132.43	153.1	98.82	142.41	180.71	210.5	137.87	158.63	184.71	213.38	116.91	137.72	168.46	202.71	81.94	104.12	123.9	148.16	124.36	159.56	205.93	249.24	86.72	109.14	136.67	175.41	81.98	96	115.03	130.96	135.13	153.89	173.25	196.02	110.32	132.14	144.78	158.53	119.07	152.19	183.38	210.94	87.89	112.15	136.9	181.11	84.1	102.58	121.96	135.54
IL1F10	ENSG00000136697	0	0	0	0	0	0	0	0.03	0.13	0	0	0	0	0	0	0.06	0.18	0	0	0	0	0	0	0	0.02	0	0	0	0.02	0	0.02	0.13	0.41	0	0	0	0	0.06	0.26	1.21	3.4	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0.05	0	0.04	0.13	0.34	0	0	0	0.03	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0.09	0	0	0	0.02	0	0	0	0	0	0	0	0.03	0	0	0	0.02	0	0	0	0.02	0	0	0.02	0.04	0	0	0	0	0	0	0	0.03	0	0	0	0	0	0	0	0
ATP13A5	ENSG00000187527	1	0	0.05	0.12	0.19	0	0	0.03	0.11	0.06	0.24	0.96	3.5	0	0.08	0.33	1.24	0.01	0.04	0.12	0.72	0	0	0	0.04	0	0	0.03	0.08	0.01	0.07	0.19	0.98	0.44	0.89	1.6	3.16	0.01	0.07	0.29	1.17	0.01	0.25	0.75	1.84	0	0.01	0.04	0.09	0	0	0.03	0.06	0	0	0	0.03	0.69	1.21	1.96	3.35	0	0	0	0	0.04	0.12	0.35	0.74	0.07	0.25	0.94	4.24	0	0	0.04	0.1	0	0.03	0.07	0.13	0.01	0.04	0.09	0.17	0	0.03	0.08	0.17	0	0	0.01	0.04	0	0	0.01	0.03	0	0	0.03	0.08	0	0	0.03	0.1	0	0.01	0.05	0.12	0	0.04	0.1	0.28	0.13	0.22	0.38	0.61	0	0.02	0.04	0.08	0	0.03	0.09	0.23	0.03	0.1	0.27	0.61	0	0	0.04	0.09
SLC22A25	ENSG00000196600	1	0	0	0	0	0	0	0	0.02	0	0	0.01	0.04	0	0	0.01	0.03	0	0.02	0.16	0.46	0	0	0	0	0	0	0.01	0.02	0	0.01	0.03	0.06	0	0	0.02	0.03	0	0	0.02	0.04	0	0	0.02	0.06	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0.01	0.03	0.7	2.07	3.79	6.88	0	0	0	0.01	0	0	0.02	0.04	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0.02	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0
OPRD1	ENSG00000116329	0	0.01	0.01	0.02	0.04	0.01	0.02	0.04	0.07	0.03	0.07	0.28	0.89	0.01	0.02	0.03	0.06	0.01	0.01	0.02	0.04	0.01	0.03	0.09	0.34	0.04	0.06	0.1	0.13	0.01	0.02	0.06	0.17	0.07	0.15	0.34	0.64	0	0.01	0.02	0.04	0.02	0.04	0.06	0.09	0.03	0.05	0.07	0.11	0.04	0.07	0.11	0.15	0.06	0.1	0.15	0.25	0.08	0.17	0.42	1.18	0.01	0.01	0.03	0.05	0.03	0.06	0.14	0.47	0.01	0.02	0.04	0.07	0.03	0.04	0.09	0.14	0.02	0.03	0.05	0.08	0.03	0.05	0.12	0.23	0.13	0.58	1.49	2.36	0.01	0.02	0.05	0.12	0.01	0.03	0.13	0.33	0.01	0.02	0.04	0.09	0.06	0.26	1.01	2.6	0.01	0.03	0.08	0.22	0.08	0.15	0.3	0.43	0.01	0.02	0.03	0.04	0.02	0.02	0.04	0.05	0.02	0.04	0.08	0.14	0.08	0.22	0.44	0.65	0	0.01	0.02	0.03
SERPINB11	ENSG00000206072	1	0	0	0	0	0	0.03	0.14	0.99	0	0	0	0.01	0.04	0.21	1.14	5.3	0	0	0	0	0	0	0	0.01	0	0	0	0.03	0	0.07	1.14	6.31	0	0	0	0	0.07	0.44	2.02	7.23	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0	0	0	0	0	0	0	0.01	0	0	0	0.05	0	0	0.08	0.37	0.05	0.38	2.25	6.42	0	0	0	0.02	0	0	0	0.01	0	0	0.05	0.26	0	0	0	0	0.25	1.44	6.64	23.08	0	0	0	0.01	0	0	0	0.04	0	0	0	0.05	0	0	0.02	0.08	0	0	0	0.04	0	0	0	0.03	0	0	0	0.04	0	0	0.02	0.06	0	0	0.03	0.09	0	0	0	0

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