Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 95 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| ENHO | ENSG00000168913 | 0.00 | 0.00 | 0 | 0 |
| INPP5D | ENSG00000168918 | 0.00 | 0.72 | 0 | 3 |
| CTRB1 | ENSG00000168925 | 0.00 | 0.00 | 0 | 0 |
| CTRB2 | ENSG00000168928 | 0.00 | 0.00 | 0 | 0 |
| PPIC | ENSG00000168938 | 0.00 | 0.00 | 0 | 0 |
| GRM5 | ENSG00000168959 | 0.00 | 0.00 | 0 | 0 |
| LGALS9 | ENSG00000168961 | 0.00 | 0.00 | 0 | 0 |
| MFSD7 | ENSG00000169026 | 0.42 | 0.00 | 1 | 0 |
| DHRSX | ENSG00000169084 | 0.00 | 0.00 | 0 | 0 |
| SLC25A6 | ENSG00000169100 | 0.00 | 0.00 | 0 | 0 |
| PCSK9 | ENSG00000169174 | 0.00 | 0.00 | 0 | 0 |
| IL13 | ENSG00000169194 | 0.00 | 0.00 | 0 | 0 |
| OR10G3 | ENSG00000169208 | 0.00 | 0.00 | 0 | 0 |
| OR6F1 | ENSG00000169214 | 0.00 | 0.00 | 0 | 0 |
| RSPO1 | ENSG00000169218 | 0.00 | 0.00 | 0 | 0 |
| CA5B | ENSG00000169239 | 0.11 | 0.00 | 1 | 0 |
| CXCL10 | ENSG00000169245 | 0.00 | 0.00 | 0 | 0 |
| CXCL11 | ENSG00000169248 | 0.00 | 0.00 | 0 | 0 |
| ADRB2 | ENSG00000169252 | 0.00 | 0.14 | 0 | 1 |
| KCNAB1 | ENSG00000169282 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 95 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.