Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 93 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| OR5I1 | ENSG00000167825 | 0.00 | 0.00 | 0 | 0 |
| CD300C | ENSG00000167850 | 0.00 | 0.00 | 0 | 0 |
| CD300A | ENSG00000167851 | 0.00 | 0.00 | 0 | 0 |
| CYP7A1 | ENSG00000167910 | 0.00 | 0.00 | 0 | 0 |
| ITFG3 | ENSG00000167930 | 0.00 | 0.14 | 0 | 1 |
| SOST | ENSG00000167941 | 0.00 | 0.00 | 0 | 0 |
| DNASE1L2 | ENSG00000167968 | 0.00 | 0.00 | 0 | 0 |
| SLC22A11 | ENSG00000168065 | 0.00 | 0.00 | 0 | 0 |
| PBK | ENSG00000168078 | 0.00 | 0.39 | 0 | 3 |
| SCARA5 | ENSG00000168079 | 0.00 | 0.00 | 0 | 0 |
| PNOC | ENSG00000168081 | 0.00 | 0.00 | 0 | 0 |
| OR1F1 | ENSG00000168124 | 0.00 | 0.00 | 0 | 0 |
| OR2W6P | ENSG00000168126 | 0.00 | 0.00 | 0 | 0 |
| OR2B2 | ENSG00000168131 | 0.00 | 0.00 | 0 | 0 |
| OR2C1 | ENSG00000168158 | 0.00 | 0.00 | 0 | 0 |
| PTGDR | ENSG00000168229 | 0.00 | 0.00 | 0 | 0 |
| KCNV2 | ENSG00000168263 | 0.00 | 0.00 | 0 | 0 |
| CX3CR1 | ENSG00000168329 | 0.00 | 0.00 | 0 | 0 |
| TAP1 | ENSG00000168394 | 0.00 | 0.00 | 0 | 0 |
| ING5 | ENSG00000168395 | 0.00 | 2.36 | 0 | 9 |
|
Showing page 93 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.