Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 74 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| FZD7 | ENSG00000155760 | 0.00 | 0.00 | 0 | 0 |
| SLC26A2 | ENSG00000155850 | 0.31 | 0.14 | 1 | 1 |
| NAT2 | ENSG00000156006 | 0.00 | 0.29 | 0 | 2 |
| DCK | ENSG00000156136 | 0.00 | 0.00 | 0 | 0 |
| SLC28A1 | ENSG00000156222 | 0.00 | 0.00 | 0 | 0 |
| CXCL13 | ENSG00000156234 | 0.00 | 0.00 | 0 | 0 |
| CDK20 | ENSG00000156345 | 0.00 | 0.15 | 0 | 1 |
| KCNS2 | ENSG00000156486 | 0.00 | 0.00 | 0 | 0 |
| HKDC1 | ENSG00000156510 | 0.00 | 0.00 | 0 | 0 |
| TYSND1 | ENSG00000156521 | 0.00 | 0.00 | 0 | 0 |
| PHF6 | ENSG00000156531 | 0.16 | 0.00 | 1 | 0 |
| CD109 | ENSG00000156535 | 0.00 | 0.00 | 0 | 0 |
| NODAL | ENSG00000156574 | 0.00 | 0.00 | 0 | 0 |
| MAPK13 | ENSG00000156711 | 0.00 | 0.00 | 0 | 0 |
| MS4A1 | ENSG00000156738 | 0.00 | 0.00 | 0 | 0 |
| FRRS1 | ENSG00000156869 | 0.00 | 0.23 | 0 | 2 |
| ITGAD | ENSG00000156886 | 0.00 | 0.00 | 0 | 0 |
| ADGRG4 | ENSG00000156920 | 0.00 | 0.00 | 0 | 0 |
| PDE6D | ENSG00000156973 | 0.00 | 1.23 | 0 | 5 |
| BRPF1 | ENSG00000156983 | 0.00 | 0.36 | 0 | 2 |
|
Showing page 74 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.