Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 294 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| PIGK | ENSG00000142892 | 0.00 | 0.00 | 0 | 0 |
| SLC25A36 | ENSG00000114120 | 0.00 | 0.00 | 0 | 0 |
| NPTN | ENSG00000156642 | 0.00 | 0.00 | 0 | 0 |
| PRDM5 | ENSG00000138738 | 0.00 | 0.00 | 0 | 0 |
| LPO | ENSG00000167419 | 0.00 | 0.00 | 0 | 0 |
| LAP3 | ENSG00000002549 | 0.00 | 0.00 | 0 | 0 |
| RHD | ENSG00000187010 | 0.00 | 0.00 | 0 | 0 |
| SENP1 | ENSG00000079387 | 0.00 | 0.00 | 0 | 0 |
| CRAT | ENSG00000095321 | 0.00 | 0.00 | 0 | 0 |
| PDE11A | ENSG00000128655 | 0.00 | 0.00 | 0 | 0 |
| MAPK8 | ENSG00000107643 | 0.00 | 0.00 | 0 | 0 |
| GABRA2 | ENSG00000151834 | 0.00 | 0.00 | 0 | 0 |
| CA1 | ENSG00000133742 | 0.00 | 0.00 | 0 | 0 |
| SLC41A3 | ENSG00000114544 | 0.00 | 0.00 | 0 | 0 |
| STK19 | ENSG00000204344 | 0.00 | 0.00 | 0 | 0 |
| USP1 | ENSG00000162607 | 0.00 | 0.00 | 0 | 0 |
| PHF8 | ENSG00000172943 | 0.00 | 0.00 | 0 | 0 |
| SMYD5 | ENSG00000135632 | 0.00 | 0.00 | 0 | 0 |
| ADAM10 | ENSG00000137845 | 0.00 | 0.00 | 0 | 0 |
| PARP6 | ENSG00000137817 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 294 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.