Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 191 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| SLC10A7 | ENSG00000120519 | 0.00 | 0.00 | 0 | 0 |
| BMP6 | ENSG00000153162 | 0.00 | 0.00 | 0 | 0 |
| SLC34A2 | ENSG00000157765 | 0.00 | 0.00 | 0 | 0 |
| ITGA11 | ENSG00000137809 | 0.00 | 0.00 | 0 | 0 |
| MMRN1 | ENSG00000138722 | 0.00 | 0.00 | 0 | 0 |
| CADM3 | ENSG00000162706 | 0.00 | 0.00 | 0 | 0 |
| DNMT3B | ENSG00000088305 | 0.00 | 0.00 | 0 | 0 |
| CCDC3 | ENSG00000151468 | 0.00 | 0.00 | 0 | 0 |
| STAT3 | ENSG00000168610 | 0.00 | 0.20 | 0 | 1 |
| KLHL32 | ENSG00000186231 | 0.00 | 0.00 | 0 | 0 |
| ADGRF5 | ENSG00000069122 | 0.00 | 0.00 | 0 | 0 |
| ST14 | ENSG00000149418 | 0.00 | 1.00 | 0 | 5 |
| SLC12A8 | ENSG00000221955 | 0.00 | 0.00 | 0 | 0 |
| PTH2R | ENSG00000144407 | 0.00 | 0.00 | 0 | 0 |
| FKBP10 | ENSG00000141756 | 0.00 | 0.00 | 0 | 0 |
| NR5A1 | ENSG00000136931 | 0.00 | 0.00 | 0 | 0 |
| C1QTNF6 | ENSG00000133466 | 0.00 | 0.00 | 0 | 0 |
| SMG1 | ENSG00000157106 | 0.00 | 0.00 | 0 | 0 |
| SPP1 | ENSG00000118785 | 0.00 | 0.00 | 0 | 0 |
| ITGA10 | ENSG00000143127 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 191 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.