Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 148 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| IGKV5-2 | ENSG00000211599 | 0.00 | 0.00 | 0 | 0 |
| IGLV4-69 | ENSG00000211637 | 0.00 | 0.00 | 0 | 0 |
| IGLV4-60 | ENSG00000211639 | 0.00 | 0.00 | 0 | 0 |
| IGLV10-54 | ENSG00000211642 | 0.00 | 0.00 | 0 | 0 |
| IGLV1-51 | ENSG00000211644 | 0.00 | 0.00 | 0 | 0 |
| IGLV7-46 | ENSG00000211649 | 0.00 | 0.00 | 0 | 0 |
| IGLV5-45 | ENSG00000211650 | 0.00 | 0.00 | 0 | 0 |
| IGLV1-44 | ENSG00000211651 | 0.00 | 0.00 | 0 | 0 |
| IGLV7-43 | ENSG00000211652 | 0.00 | 0.00 | 0 | 0 |
| IGLV1-40 | ENSG00000211653 | 0.00 | 0.00 | 0 | 0 |
| IGLV1-36 | ENSG00000211655 | 0.00 | 0.00 | 0 | 0 |
| IGLV3-27 | ENSG00000211658 | 0.00 | 0.00 | 0 | 0 |
| IGLV3-25 | ENSG00000211659 | 0.00 | 0.00 | 0 | 0 |
| IGLV2-23 | ENSG00000211660 | 0.00 | 0.00 | 0 | 0 |
| IGLV2-11 | ENSG00000211668 | 0.00 | 0.00 | 0 | 0 |
| IGLC2 | ENSG00000211677 | 0.00 | 0.00 | 0 | 0 |
| IGLC3 | ENSG00000211679 | 0.00 | 0.00 | 0 | 0 |
| IGHA2 | ENSG00000211890 | 0.00 | 0.14 | 0 | 1 |
| IGHE | ENSG00000211891 | 0.00 | 0.00 | 0 | 0 |
| IGHG4 | ENSG00000211892 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 148 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.