Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 145 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| HLA-G | ENSG00000204632 | 0.00 | 0.00 | 0 | 0 |
| NMS | ENSG00000204640 | 0.00 | 0.00 | 0 | 0 |
| OR2H2 | ENSG00000204657 | 0.00 | 0.00 | 0 | 0 |
| IL31 | ENSG00000204671 | 0.00 | 0.00 | 0 | 0 |
| AKT1S1 | ENSG00000204673 | 0.00 | 0.32 | 0 | 1 |
| GABBR1 | ENSG00000204681 | 0.00 | 0.00 | 0 | 0 |
| MAS1L | ENSG00000204687 | 0.00 | 0.00 | 0 | 0 |
| OR11A1 | ENSG00000204694 | 0.00 | 0.00 | 0 | 0 |
| OR14J1 | ENSG00000204695 | 0.00 | 0.00 | 0 | 0 |
| OR2J2 | ENSG00000204700 | 0.00 | 0.00 | 0 | 0 |
| OR2J3 | ENSG00000204701 | 0.00 | 0.00 | 0 | 0 |
| OR2J1 | ENSG00000204702 | 0.00 | 0.00 | 0 | 0 |
| OR2B3 | ENSG00000204703 | 0.00 | 0.00 | 0 | 0 |
| OR2W1 | ENSG00000204704 | 0.00 | 0.00 | 0 | 0 |
| GPR20 | ENSG00000204882 | 0.00 | 0.00 | 0 | 0 |
| SPINK9 | ENSG00000204909 | 0.00 | 0.00 | 0 | 0 |
| UQCC3 | ENSG00000204922 | 0.11 | 0.00 | 1 | 0 |
| CD177 | ENSG00000204936 | 0.00 | 0.28 | 0 | 1 |
| PRSS3P4 | ENSG00000204982 | 0.00 | 0.00 | 0 | 0 |
| OR5D16 | ENSG00000205029 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 145 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.