Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 142 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| OR10R3P | ENSG00000198703 | 0.00 | 0.00 | 0 | 0 |
| MT-CO2 | ENSG00000198712 | 0.00 | 0.00 | 0 | 0 |
| SLC5A3 | ENSG00000198743 | 0.00 | 0.00 | 0 | 0 |
| GRIN3A | ENSG00000198785 | 0.00 | 0.00 | 0 | 0 |
| MUC2 | ENSG00000198788 | 0.00 | 0.00 | 0 | 0 |
| PNP | ENSG00000198805 | 0.00 | 0.10 | 0 | 1 |
| CES1 | ENSG00000198848 | 0.12 | 0.00 | 1 | 0 |
| CD3E | ENSG00000198851 | 0.00 | 0.23 | 0 | 1 |
| STKLD1 | ENSG00000198870 | 0.00 | 0.00 | 0 | 0 |
| OR5D13 | ENSG00000198877 | 0.00 | 0.00 | 0 | 0 |
| MT-ND4 | ENSG00000198886 | 0.00 | 0.00 | 0 | 0 |
| PRMT6 | ENSG00000198890 | 0.00 | 0.58 | 0 | 3 |
| MT-ATP6 | ENSG00000198899 | 0.00 | 0.00 | 0 | 0 |
| L1CAM | ENSG00000198910 | 0.00 | 0.00 | 0 | 0 |
| APRT | ENSG00000198931 | 0.00 | 0.81 | 0 | 5 |
| DMD | ENSG00000198947 | 0.00 | 0.11 | 0 | 1 |
| NAGA | ENSG00000198951 | 0.00 | 0.23 | 0 | 1 |
| TGM2 | ENSG00000198959 | 0.00 | 0.00 | 0 | 0 |
| OR10R2 | ENSG00000198965 | 0.00 | 0.00 | 0 | 0 |
| OR10Z1 | ENSG00000198967 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 142 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.