Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 125 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| OR10J5 | ENSG00000184155 | 0.00 | 0.00 | 0 | 0 |
| ADRA2C | ENSG00000184160 | 0.00 | 0.00 | 0 | 0 |
| OR1D2 | ENSG00000184166 | 0.00 | 0.00 | 0 | 0 |
| GPR173 | ENSG00000184194 | 0.00 | 0.00 | 0 | 0 |
| KCNK12 | ENSG00000184261 | 0.00 | 0.00 | 0 | 0 |
| DEFB108B | ENSG00000184276 | 0.00 | 0.00 | 0 | 0 |
| DRD5P1 | ENSG00000184303 | 0.00 | 0.00 | 0 | 0 |
| OR51J1 | ENSG00000184321 | 0.00 | 0.00 | 0 | 0 |
| SRPK3 | ENSG00000184343 | 0.00 | 0.00 | 0 | 0 |
| CSF1 | ENSG00000184371 | 0.00 | 0.47 | 0 | 2 |
| OR4N5 | ENSG00000184394 | 0.00 | 0.00 | 0 | 0 |
| KCND2 | ENSG00000184408 | 0.00 | 0.00 | 0 | 0 |
| TOP1MT | ENSG00000184428 | 0.94 | 0.00 | 3 | 0 |
| CCR10 | ENSG00000184451 | 0.00 | 0.00 | 0 | 0 |
| C1QTNF8 | ENSG00000184471 | 0.00 | 0.00 | 0 | 0 |
| OR56A3 | ENSG00000184478 | 0.00 | 0.00 | 0 | 0 |
| GAST | ENSG00000184502 | 0.00 | 0.00 | 0 | 0 |
| DHRS7C | ENSG00000184544 | 0.00 | 0.00 | 0 | 0 |
| DUSP8 | ENSG00000184545 | 0.00 | 0.41 | 0 | 3 |
| LPAR5 | ENSG00000184574 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 125 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.