Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 122 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| OR4Q3 | ENSG00000182652 | 0.00 | 0.00 | 0 | 0 |
| GALR2 | ENSG00000182687 | 0.00 | 0.00 | 0 | 0 |
| IGIP | ENSG00000182700 | 0.30 | 0.14 | 1 | 1 |
| SLC35D3 | ENSG00000182747 | 0.00 | 0.00 | 0 | 0 |
| PAPPA | ENSG00000182752 | 0.00 | 0.00 | 0 | 0 |
| HCAR2 | ENSG00000182782 | 0.00 | 0.00 | 0 | 0 |
| OR2T29 | ENSG00000182783 | 0.00 | 0.00 | 0 | 0 |
| VMO1 | ENSG00000182853 | 0.00 | 0.12 | 0 | 1 |
| OR4F15 | ENSG00000182854 | 0.00 | 0.00 | 0 | 0 |
| ADGRG3 | ENSG00000182885 | 0.00 | 0.00 | 0 | 0 |
| SLC25A18 | ENSG00000182902 | 0.00 | 0.00 | 0 | 0 |
| SPNS2 | ENSG00000183018 | 0.00 | 0.13 | 0 | 1 |
| OR1G1 | ENSG00000183024 | 0.00 | 0.00 | 0 | 0 |
| SLC25A21 | ENSG00000183032 | 0.48 | 0.00 | 2 | 0 |
| SLC25A10 | ENSG00000183048 | 0.63 | 0.00 | 3 | 0 |
| FREM3 | ENSG00000183090 | 0.00 | 0.00 | 0 | 0 |
| PTGDR2 | ENSG00000183134 | 0.00 | 0.00 | 0 | 0 |
| GABRR3 | ENSG00000183185 | 0.00 | 0.00 | 0 | 0 |
| CHST6 | ENSG00000183196 | 0.00 | 0.00 | 0 | 0 |
| OR51B4 | ENSG00000183251 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 122 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.