Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 113 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| KCNA2 | ENSG00000177301 | 0.00 | 0.00 | 0 | 0 |
| OR7E125P | ENSG00000177306 | 0.00 | 0.00 | 0 | 0 |
| OR7E8P | ENSG00000177400 | 0.00 | 0.00 | 0 | 0 |
| NIM1K | ENSG00000177453 | 0.00 | 0.00 | 0 | 0 |
| OR2T8 | ENSG00000177462 | 0.00 | 0.00 | 0 | 0 |
| GPR4 | ENSG00000177464 | 0.00 | 0.00 | 0 | 0 |
| OR2G3 | ENSG00000177476 | 0.00 | 0.00 | 0 | 0 |
| OR2G2 | ENSG00000177489 | 0.00 | 0.00 | 0 | 0 |
| OR2B11 | ENSG00000177535 | 0.00 | 0.00 | 0 | 0 |
| SLC25A22 | ENSG00000177542 | 0.00 | 0.40 | 0 | 3 |
| CD163 | ENSG00000177575 | 0.00 | 0.00 | 0 | 0 |
| GSG2 | ENSG00000177602 | 0.00 | 0.00 | 0 | 0 |
| JUN | ENSG00000177606 | 0.65 | 0.00 | 1 | 0 |
| MBOAT4 | ENSG00000177669 | 0.00 | 0.00 | 0 | 0 |
| CD163L1 | ENSG00000177675 | 0.00 | 0.00 | 0 | 0 |
| DEFB114 | ENSG00000177684 | 0.00 | 0.00 | 0 | 0 |
| OR4F4 | ENSG00000177693 | 0.00 | 0.00 | 0 | 0 |
| FAM20C | ENSG00000177706 | 0.00 | 0.00 | 0 | 0 |
| SLC35G5 | ENSG00000177710 | 0.00 | 0.00 | 0 | 0 |
| UBE2N | ENSG00000177889 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 113 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.