Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 100 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| FPR1 | ENSG00000171051 | 0.00 | 0.00 | 0 | 0 |
| OR13H1 | ENSG00000171054 | 0.00 | 0.00 | 0 | 0 |
| OBP2B | ENSG00000171102 | 0.00 | 0.24 | 0 | 1 |
| NRTN | ENSG00000171119 | 0.00 | 0.00 | 0 | 0 |
| ATP6V0E2 | ENSG00000171130 | 0.11 | 0.19 | 1 | 1 |
| OR2K2 | ENSG00000171133 | 0.00 | 0.00 | 0 | 0 |
| RLN3 | ENSG00000171136 | 0.00 | 0.00 | 0 | 0 |
| OR2M4 | ENSG00000171180 | 0.00 | 0.00 | 0 | 0 |
| GRIK1 | ENSG00000171189 | 0.00 | 0.00 | 0 | 0 |
| MUC7 | ENSG00000171195 | 0.00 | 0.00 | 0 | 0 |
| SMR3B | ENSG00000171201 | 0.00 | 0.00 | 0 | 0 |
| CSN3 | ENSG00000171209 | 0.00 | 0.00 | 0 | 0 |
| LRG1 | ENSG00000171236 | 0.00 | 0.00 | 0 | 0 |
| SOSTDC1 | ENSG00000171243 | 0.00 | 0.00 | 0 | 0 |
| KCND3 | ENSG00000171385 | 0.00 | 0.00 | 0 | 0 |
| APLN | ENSG00000171388 | 0.00 | 0.00 | 0 | 0 |
| NAT1 | ENSG00000171428 | 0.00 | 0.55 | 0 | 4 |
| POLR1C | ENSG00000171453 | 0.31 | 0.00 | 2 | 0 |
| OR1L6 | ENSG00000171459 | 0.00 | 0.00 | 0 | 0 |
| SPACA5B | ENSG00000171478 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 100 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.