Copy Number
The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).
| Showing page 10 |
first page | previous page | next page | last page |
| Overall_Gscore | No. of Cancer Types | ||||
| HGNC Symbol | Ensembl Gene ID | Amplification | Deletion | Amplification | Deletion |
| ARAF | ENSG00000078061 | 0.00 | 0.00 | 0 | 0 |
| EDN1 | ENSG00000078401 | 0.00 | 0.00 | 0 | 0 |
| FGF20 | ENSG00000078579 | 0.00 | 0.00 | 0 | 0 |
| P2RY10 | ENSG00000078589 | 0.00 | 0.00 | 0 | 0 |
| PKD2L2 | ENSG00000078795 | 0.00 | 0.00 | 0 | 0 |
| BPIFB2 | ENSG00000078898 | 0.00 | 0.00 | 0 | 0 |
| LXN | ENSG00000079257 | 0.00 | 0.00 | 0 | 0 |
| LIPE | ENSG00000079435 | 0.00 | 0.28 | 0 | 1 |
| AFM | ENSG00000079557 | 0.00 | 0.00 | 0 | 0 |
| MOXD1 | ENSG00000079931 | 0.00 | 0.12 | 0 | 1 |
| DCT | ENSG00000080166 | 0.00 | 0.00 | 0 | 0 |
| SLC35C2 | ENSG00000080189 | 0.13 | 0.00 | 1 | 0 |
| EPHA6 | ENSG00000080224 | 0.00 | 0.00 | 0 | 0 |
| SCTR | ENSG00000080293 | 0.00 | 0.00 | 0 | 0 |
| KCNN2 | ENSG00000080709 | 0.00 | 0.00 | 0 | 0 |
| MOK | ENSG00000080823 | 0.17 | 0.00 | 1 | 0 |
| CXCL2 | ENSG00000081041 | 0.00 | 0.00 | 0 | 0 |
| AFP | ENSG00000081051 | 0.00 | 0.00 | 0 | 0 |
| COL4A4 | ENSG00000081052 | 0.00 | 0.19 | 0 | 1 |
| SLC13A1 | ENSG00000081800 | 0.00 | 0.00 | 0 | 0 |
|
Showing page 10 |
first page | previous page | next page | last page |
Copyright © 2020 University of Pennsylvania. All Rights Reserved.